BDBM304041 US10138245, Example 48B

SMILES: Cc1cc(C)n2nc(nc2n1)-c1ccc2nc(-c3ccccc3)n(C)c2c1

InChI Key: InChIKey=DVODXTQTLQUZGR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM304041 (US10138245, Example 48B) Show SMILES Cc1cc(C)n2nc(nc2n1)-c1ccc2nc(-c3ccccc3)n(C)c2c1 Show InChI InChI=1S/C21H18N6/c1-13-11-14(2)27-21(22-13)24-19(25-27)16-9-10-17-18(12-16)26(3)20(23-17)15-7-5-4-6-8-15/h4-12H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	413	n/a	n/a	n/a	n/a	n/a	n/a
CELON PHARMA S.A. US Patent					Assay Description Recombinant human phosphodiesterase 10A (PDE10A) purified to homogeneity from Sf9 cells overexpressing PDE10A gene (GenBank/EMBL accession number: NM...				US Patent US10138245 (2018) BindingDB Entry DOI: 10.7270/Q2M32XTX
					More data for this Ligand-Target Pair