null

SMILES: CC(C)[C@@H]1CN(CCN1c1ncc(Cl)c(C)n1)c1ccc(F)c(c1)S(C)(=O)=O

InChI Key: InChIKey=JSVXZVWRZPKCFT-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 304338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM304338 ((R)-5-chloro-2-(4-(4-fluoro-3-(methylsulfonyl)phen...) Show SMILES CC(C)[C@@H]1CN(CCN1c1ncc(Cl)c(C)n1)c1ccc(F)c(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C19H24ClFN4O2S/c1-12(2)17-11-24(14-5-6-16(21)18(9-14)28(4,26)27)7-8-25(17)19-22-10-15(20)13(3)23-19/h5-6,9-10,12,17H,7-8,11H2,1-4H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...				US Patent US10144715 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NFD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM304338 ((R)-5-chloro-2-(4-(4-fluoro-3-(methylsulfonyl)phen...) Show SMILES CC(C)[C@@H]1CN(CCN1c1ncc(Cl)c(C)n1)c1ccc(F)c(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C19H24ClFN4O2S/c1-12(2)17-11-24(14-5-6-16(21)18(9-14)28(4,26)27)7-8-25(17)19-22-10-15(20)13(3)23-19/h5-6,9-10,12,17H,7-8,11H2,1-4H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...				US Patent US10144715 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NFD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM304338 ((R)-5-chloro-2-(4-(4-fluoro-3-(methylsulfonyl)phen...) Show SMILES CC(C)[C@@H]1CN(CCN1c1ncc(Cl)c(C)n1)c1ccc(F)c(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C19H24ClFN4O2S/c1-12(2)17-11-24(14-5-6-16(21)18(9-14)28(4,26)27)7-8-25(17)19-22-10-15(20)13(3)23-19/h5-6,9-10,12,17H,7-8,11H2,1-4H3/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	677	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description This assay is based on the ability of the LXR-LBDs (LXRα and LXRβ) to recruit and interact with a co-activator peptide. This assay was run ...				US Patent US10144715 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NFD
					More data for this Ligand-Target Pair