BDBM304529 (R)-1-(6-cyclopropyl-5-(trifluoromethyl)pyridin-2-yl)-2-isopropyl-4-(3-(methylsulfonyl)phenyl)piperazine::US10144715, Compound 40-4

SMILES: CC(C)[C@@H]1CN(CCN1c1ccc(c(n1)C1CC1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O

InChI Key: InChIKey=NSWRBHFZGBXSGU-FQEVSTJZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304529   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM304529 ((R)-1-(6-cyclopropyl-5-(trifluoromethyl)pyridin-2-...) Show SMILES CC(C)[C@@H]1CN(CCN1c1ccc(c(n1)C1CC1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C23H28F3N3O2S/c1-15(2)20-14-28(17-5-4-6-18(13-17)32(3,30)31)11-12-29(20)21-10-9-19(23(24,25)26)22(27-21)16-7-8-16/h4-6,9-10,13,15-16,20H,7-8,11-12,14H2,1-3H3/t20-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...				US Patent US10144715 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NFD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM304529 ((R)-1-(6-cyclopropyl-5-(trifluoromethyl)pyridin-2-...) Show SMILES CC(C)[C@@H]1CN(CCN1c1ccc(c(n1)C1CC1)C(F)(F)F)c1cccc(c1)S(C)(=O)=O |r| Show InChI InChI=1S/C23H28F3N3O2S/c1-15(2)20-14-28(17-5-4-6-18(13-17)32(3,30)31)11-12-29(20)21-10-9-19(23(24,25)26)22(27-21)16-7-8-16/h4-6,9-10,13,15-16,20H,7-8,11-12,14H2,1-3H3/t20-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc. US Patent					Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...				US Patent US10144715 (2018) BindingDB Entry DOI: 10.7270/Q2PV6NFD
					More data for this Ligand-Target Pair