BDBM307562 5-(2-(4-Fluorophenyl)-3-(methylcarbamoyl)-6-(2,2,2-trifluoroethoxy)benzofuran-5-yl)-2-methoxy-N-(1-(pyrimidin-2-yl)cyclopropyl)nicotinamide::US10150747, Example 29

SMILES: CNC(=O)c1c(oc2cc(OCC(F)(F)F)c(cc12)-c1cnc(OC)c(c1)C(=O)NC1(CC1)c1ncccn1)-c1ccc(F)cc1

InChI Key: InChIKey=YVNPBSXRQIPGDF-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA polymerase (NS5B) (Hepatitis C virus (HCV))	BDBM307562 (5-(2-(4-Fluorophenyl)-3-(methylcarbamoyl)-6-(2,2,2...) Show SMILES CNC(=O)c1c(oc2cc(OCC(F)(F)F)c(cc12)-c1cnc(OC)c(c1)C(=O)NC1(CC1)c1ncccn1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H25F4N5O5/c1-37-28(43)25-21-13-20(23(45-16-32(34,35)36)14-24(21)46-26(25)17-4-6-19(33)7-5-17)18-12-22(29(44-2)40-15-18)27(42)41-31(8-9-31)30-38-10-3-11-39-30/h3-7,10-15H,8-9,16H2,1-2H3,(H,37,43)(H,41,42)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.57	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10150747 (2018) BindingDB Entry DOI: 10.7270/Q2H70HWJ
					More data for this Ligand-Target Pair
RNA polymerase (NS5B) (Hepatitis C virus (HCV))	BDBM307562 (5-(2-(4-Fluorophenyl)-3-(methylcarbamoyl)-6-(2,2,2...) Show SMILES CNC(=O)c1c(oc2cc(OCC(F)(F)F)c(cc12)-c1cnc(OC)c(c1)C(=O)NC1(CC1)c1ncccn1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H25F4N5O5/c1-37-28(43)25-21-13-20(23(45-16-32(34,35)36)14-24(21)46-26(25)17-4-6-19(33)7-5-17)18-12-22(29(44-2)40-15-18)27(42)41-31(8-9-31)30-38-10-3-11-39-30/h3-7,10-15H,8-9,16H2,1-2H3,(H,37,43)(H,41,42)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.95	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...				US Patent US10150747 (2018) BindingDB Entry DOI: 10.7270/Q2H70HWJ
					More data for this Ligand-Target Pair