BDBM307720 (3R)-N-{5-chloro-4-[1-(4-fluorobenzyl)-1H-benzimidazol-6-yl]pyridin-2-yl}piperidine-3-carboxamide::US9650358, Example 16

SMILES: Fc1ccc(Cn2cnc3ccc(cc23)-c2cc(NC(=O)[C@@H]3CCCNC3)ncc2Cl)cc1

InChI Key: InChIKey=SNIFYDOZOYQPDU-GOSISDBHSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307720   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM307720 ( (3R)-N-{5-chloro-4-[1-(4-fluorobenzyl)-1H-benzimi...) Show SMILES Fc1ccc(Cn2cnc3ccc(cc23)-c2cc(NC(=O)[C@@H]3CCCNC3)ncc2Cl)cc1 Show InChI InChI=1S/C25H23ClFN5O/c26-21-13-29-24(31-25(33)18-2-1-9-28-12-18)11-20(21)17-5-8-22-23(10-17)32(15-30-22)14-16-3-6-19(27)7-4-16/h3-8,10-11,13,15,18,28H,1-2,9,12,14H2,(H,29,31,33)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. US Patent					Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...				US Patent US9650358 (2017) BindingDB Entry DOI: 10.7270/Q2057J0M
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