BDBM308049 US10011593, Ex. 1::US9650366, 1

SMILES: FC(F)(F)c1cc(NC(=O)Nc2ccc3sc(cc3c2)-c2cncc(c2)-c2nn[nH]n2)ccc1Cl

InChI Key: InChIKey=MUQOSCBBZLPHPJ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 308049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interferon-induced, double-stranded RNA-activated protein kinase (Homo sapiens (Human))	BDBM308049 (US10011593, Ex. 1 | US9650366, 1) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc3sc(cc3c2)-c2cncc(c2)-c2nn[nH]n2)ccc1Cl Show InChI InChI=1S/C22H13ClF3N7OS/c23-17-3-1-15(8-16(17)22(24,25)26)29-21(34)28-14-2-4-18-11(6-14)7-19(35-18)12-5-13(10-27-9-12)20-30-32-33-31-20/h1-10H,(H2,28,29,34)(H,30,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	727	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...				US Patent US9650366 (2017) BindingDB Entry DOI: 10.7270/Q2QN68VG
					More data for this Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase (Homo sapiens (Human))	BDBM308049 (US10011593, Ex. 1 | US9650366, 1) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc3sc(cc3c2)-c2cncc(c2)-c2nn[nH]n2)ccc1Cl Show InChI InChI=1S/C22H13ClF3N7OS/c23-17-3-1-15(8-16(17)22(24,25)26)29-21(34)28-14-2-4-18-11(6-14)7-19(35-18)12-5-13(10-27-9-12)20-30-32-33-31-20/h1-10H,(H2,28,29,34)(H,30,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	727	n/a	n/a	n/a	n/a	n/a	n/a
Vertex					Assay Description PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...				J Med Chem 52: 6362-8 (2009) BindingDB Entry DOI: 10.7270/Q24J0HGV
					More data for this Ligand-Target Pair