BDBM308072 US9650371, 33
SMILES: C[C@]1(C=CSC(N)=N1)c1cc(NC(=O)c2ccc(OCCO)cn2)ccc1F
InChI Key: InChIKey=XDFXGFOUVTXUNH-IBGZPJMESA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Beta-secretase 1 (Homo sapiens (Human)) | BDBM308072 (US9650371, 33) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd. US Patent | Assay Description 48.5 uL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well of... | US Patent US9650371 (2017) BindingDB Entry DOI: 10.7270/Q2M047HB | |||||||||||
More data for this Ligand-Target Pair |