BDBM30925 2-({[2-(1H-indol-3-yl)ethyl]amino}carbonyl)cyclohexanecarboxylic acid::2-[2-(1H-indol-3-yl)ethylcarbamoyl]cyclohexane-1-carboxylic acid::2-[2-(1H-indol-3-yl)ethylcarbamoyl]cyclohexanecarboxylic acid::2-[[2-(1H-indol-3-yl)ethylamino]-oxomethyl]-1-cyclohexanecarboxylic acid::MLS000051191::SMR000079133::cid_2965107

SMILES: OC(=O)C1CCCCC1C(=O)NCCc1c[nH]c2ccccc12

InChI Key: InChIKey=URCMCAGJCXKTIR-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 30925   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM30925 (2-({[2-(1H-indol-3-yl)ethyl]amino}carbonyl)cyclohe...) Show SMILES OC(=O)C1CCCCC1C(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C18H22N2O3/c21-17(14-6-1-2-7-15(14)18(22)23)19-10-9-12-11-20-16-8-4-3-5-13(12)16/h3-5,8,11,14-15,20H,1-2,6-7,9-10H2,(H,19,21)(H,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	9.90E+4	n/a	n/a	7.4	23
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q21N7ZG0
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM30925 (2-({[2-(1H-indol-3-yl)ethyl]amino}carbonyl)cyclohe...) Show SMILES OC(=O)C1CCCCC1C(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C18H22N2O3/c21-17(14-6-1-2-7-15(14)18(22)23)19-10-9-12-11-20-16-8-4-3-5-13(12)16/h3-5,8,11,14-15,20H,1-2,6-7,9-10H2,(H,19,21)(H,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description External Assay ID: S1P3_EC50_CS_5HT1e_Agonist Name: S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E ...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2PN941W
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM30925 (2-({[2-(1H-indol-3-yl)ethyl]amino}carbonyl)cyclohe...) Show SMILES OC(=O)C1CCCCC1C(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C18H22N2O3/c21-17(14-6-1-2-7-15(14)18(22)23)19-10-9-12-11-20-16-8-4-3-5-13(12)16/h3-5,8,11,14-15,20H,1-2,6-7,9-10H2,(H,19,21)(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	765	n/a	n/a	7.4	23
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description The CHO cell line was cultured in T-175 sq cm Corning flasks (part 431080) at 37 deg C and 95% RH. The HTS assay began by dispensing 10 microliters o...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2Q52MZM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM30925 (2-({[2-(1H-indol-3-yl)ethyl]amino}carbonyl)cyclohe...) Show SMILES OC(=O)C1CCCCC1C(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C18H22N2O3/c21-17(14-6-1-2-7-15(14)18(22)23)19-10-9-12-11-20-16-8-4-3-5-13(12)16/h3-5,8,11,14-15,20H,1-2,6-7,9-10H2,(H,19,21)(H,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	3.48E+4	n/a	n/a	7.4	23
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2WW7G03
					More data for this Ligand-Target Pair