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SMILES: NNC(=O)Cc1ccc(CCc2ccc(cc2C(F)(F)F)N2CCNCC2)cc1

InChI Key: InChIKey=JOANJVSPVUFIRJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309467   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM309467 (US9603833, Example 59) Show SMILES NNC(=O)Cc1ccc(CCc2ccc(cc2C(F)(F)F)N2CCNCC2)cc1 Show InChI InChI=1S/C21H25F3N4O/c22-21(23,24)19-14-18(28-11-9-26-10-12-28)8-7-17(19)6-5-15-1-3-16(4-2-15)13-20(29)27-25/h1-4,7-8,14,26H,5-6,9-13,25H2,(H,27,29)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM309467 (US9603833, Example 59) Show SMILES NNC(=O)Cc1ccc(CCc2ccc(cc2C(F)(F)F)N2CCNCC2)cc1 Show InChI InChI=1S/C21H25F3N4O/c22-21(23,24)19-14-18(28-11-9-26-10-12-28)8-7-17(19)6-5-15-1-3-16(4-2-15)13-20(29)27-25/h1-4,7-8,14,26H,5-6,9-13,25H2,(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.3	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
					More data for this Ligand-Target Pair