BDBM310087 2-chloro-6-fluoro-N-[1-(3-trifluoromethylbenzenesulfonyl)-1H-pyrazolo[4,3-b]pyridin-6-yl]benzamide ::US10377768, Compound 1::US9657033, Compound 1

SMILES: Fc1cccc(Cl)c1C(=O)Nc1cnc2cnn(c2c1)S(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=GQCLNPMDLGCICZ-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 310087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM310087 (2-chloro-6-fluoro-N-[1-(3-trifluoromethylbenzenesu...) Show SMILES Fc1cccc(Cl)c1C(=O)Nc1cnc2cnn(c2c1)S(=O)(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H11ClF4N4O3S/c21-14-5-2-6-15(22)18(14)19(30)28-12-8-17-16(26-9-12)10-27-29(17)33(31,32)13-4-1-3-11(7-13)20(23,24)25/h1-10H,(H,28,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a
Lycera Corporation; Merck Sharp & Dohme Corp. US Patent					Assay Description Recombinant,HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a ...				US Patent US9657033 (2017) BindingDB Entry DOI: 10.7270/Q24Q7X2T
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM310087 (2-chloro-6-fluoro-N-[1-(3-trifluoromethylbenzenesu...) Show SMILES Fc1cccc(Cl)c1C(=O)Nc1cnc2cnn(c2c1)S(=O)(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H11ClF4N4O3S/c21-14-5-2-6-15(22)18(14)19(30)28-12-8-17-16(26-9-12)10-27-29(17)33(31,32)13-4-1-3-11(7-13)20(23,24)25/h1-10H,(H,28,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Lycera Corporation US Patent					Assay Description HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...				US Patent US10377768 (2019) BindingDB Entry DOI: 10.7270/Q29P341J
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM310087 (2-chloro-6-fluoro-N-[1-(3-trifluoromethylbenzenesu...) Show SMILES Fc1cccc(Cl)c1C(=O)Nc1cnc2cnn(c2c1)S(=O)(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H11ClF4N4O3S/c21-14-5-2-6-15(22)18(14)19(30)28-12-8-17-16(26-9-12)10-27-29(17)33(31,32)13-4-1-3-11(7-13)20(23,24)25/h1-10H,(H,28,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a
Lycera Corporation US Patent					Assay Description Recombinant, HIS-tagged RORγ-LBD was expressed in SF9 cells using a baculovirus expression system. Cells were lysed and the lysate was used as a...				US Patent US10377768 (2019) BindingDB Entry DOI: 10.7270/Q29P341J
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM310087 (2-chloro-6-fluoro-N-[1-(3-trifluoromethylbenzenesu...) Show SMILES Fc1cccc(Cl)c1C(=O)Nc1cnc2cnn(c2c1)S(=O)(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H11ClF4N4O3S/c21-14-5-2-6-15(22)18(14)19(30)28-12-8-17-16(26-9-12)10-27-29(17)33(31,32)13-4-1-3-11(7-13)20(23,24)25/h1-10H,(H,28,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Lycera Corporation; Merck Sharp & Dohme Corp. US Patent					Assay Description HIS-tagged RORγ-LBD protein was expressed in SF9 cells using a baculovirus expression system. The RORγ-LBD protein was purified by glutathi...				US Patent US9657033 (2017) BindingDB Entry DOI: 10.7270/Q24Q7X2T
					More data for this Ligand-Target Pair