BDBM31036 2-[(4-phenyl-1-piperazinyl)methyl]imidazo[1,2-a]pyrimidine::2-[(4-phenylpiperazin-1-yl)methyl]imidazo[1,2-a]pyrimidine::2-[(4-phenylpiperazino)methyl]imidazo[1,2-a]pyrimidine::MLS000100989::SMR000017404::cid_916985

SMILES: C(N1CCN(CC1)c1ccccc1)c1cn2cccnc2n1

InChI Key: InChIKey=PDWPQVUNIFZQKW-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 31036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM31036 (2-[(4-phenyl-1-piperazinyl)methyl]imidazo[1,2-a]py...) Show SMILES C(N1CCN(CC1)c1ccccc1)c1cn2cccnc2n1 Show InChI InChI=1S/C17H19N5/c1-2-5-16(6-3-1)21-11-9-20(10-12-21)13-15-14-22-8-4-7-18-17(22)19-15/h1-8,14H,9-13H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	5.00E+4	n/a	n/a	7.4	23
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2WW7G03
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM31036 (2-[(4-phenyl-1-piperazinyl)methyl]imidazo[1,2-a]py...) Show SMILES C(N1CCN(CC1)c1ccccc1)c1cn2cccnc2n1 Show InChI InChI=1S/C17H19N5/c1-2-5-16(6-3-1)21-11-9-20(10-12-21)13-15-14-22-8-4-7-18-17(22)19-15/h1-8,14H,9-13H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description External Assay ID: S1P3_EC50_CS_5HT1e_Agonist Name: S1P3 Dose Response Assay Counterscreen for 5-Hydroxytryptamine(Serotonin) Receptor Subtype 1E ...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2PN941W
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM31036 (2-[(4-phenyl-1-piperazinyl)methyl]imidazo[1,2-a]py...) Show SMILES C(N1CCN(CC1)c1ccccc1)c1cn2cccnc2n1 Show InChI InChI=1S/C17H19N5/c1-2-5-16(6-3-1)21-11-9-20(10-12-21)13-15-14-22-8-4-7-18-17(22)19-15/h1-8,14H,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.07E+3	n/a	n/a	7.4	23
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description The CHO cell line was cultured in T-175 sq cm Corning flasks (part 431080) at 37 deg C and 95% RH. The HTS assay began by dispensing 10 microliters o...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2Q52MZM
					More data for this Ligand-Target Pair