null
SMILES: CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C
InChI Key: InChIKey=WVUNYSQLFKLYNI-AATRIKPKSA-N
PDB links: 2 PDB IDs match this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2GB22FT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
eIF-2-alpha kinase GCN2 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | 2.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q28W3BP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 3 of Ribosomal protein S6 kinase alpha-2 (3) (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | 8.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2CC0Z29 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [T315I] (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 860 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [G719C] (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 0.240 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 3 [1-975] (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK1 [R432A] (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | 7.4 | 23 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK4 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | 7.4 | 23 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-B receptor 4 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [N841I] (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase FRK (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 680 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835H] (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 [D835Y] (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fgr (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2JD4V4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2DN43D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q25719CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lyn (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21G0JNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase TNNI3K (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2N58JRR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 20 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2HD7T1F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2CN7293 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q28050ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2474877 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 [1-999,Q252H] (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q20G3HJZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2VQ3122 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ABL2 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QZ28BB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium/calmodulin-dependent protein kinase kinase 1 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q237773V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calcium/calmodulin-dependent protein kinase kinase 2 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2ZG6QM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK2 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2FJ2F5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase CSK (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q29S1PFT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform delta (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2610XQD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform epsilon (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q228060G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase 12 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2J964RG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2DJ5D15 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-999,L858R] (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q28S4N9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ephrin type-A receptor 8 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2RR1WM7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fer (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2CJ8BVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fes/Fps (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27S7M4M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-G-associated kinase (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q20863ND | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase HCK (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2VH5M6K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QV3JW5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2Z899SH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myosin light chain kinase 2, skeletal/cardiac muscle (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2PV6HRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interferon-induced, double-stranded RNA-activated protein kinase (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2WD3XZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2057DBF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 36 (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QN654T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2KW5DD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human)) | BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q26Q1VMH | |||||||||||
More data for this Ligand-Target Pair |
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