BDBM310925 ((5-Bromo-2-(Methoxycarbonyl)Benzo[b]Thiophen-6-yl)Difluoromethyl)Phosphonate::US10150787, Example 8

SMILES: COC(=O)c1cc2cc(Br)c(cc2s1)C(F)(F)P(O)(O)=O

InChI Key: InChIKey=NIFCOLADCGONKJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310925   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM310925 (((5-Bromo-2-(Methoxycarbonyl)Benzo[b]Thiophen-6-yl...) Show SMILES COC(=O)c1cc2cc(Br)c(cc2s1)C(F)(F)P(O)(O)=O Show InChI InChI=1S/C11H8BrF2O5PS/c1-19-10(15)9-3-5-2-7(12)6(4-8(5)21-9)11(13,14)20(16,17)18/h2-4H,1H3,(H2,16,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description The assay was carried out at room temperature in 96 well plates. The reaction mixture in 170 μl contained 50 mM Bis-Tris (pH=6.3), 2 mM EDTA, 5 ...				US Patent US10150787 (2018) BindingDB Entry DOI: 10.7270/Q2QJ7KC8
					More data for this Ligand-Target Pair