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SMILES: CC(C)C[C@](C)(N)COc1cnc(cc1C)-c1ccnc(c1)C(F)F
InChI Key: InChIKey=VYPORTDNBOGDIG-IBGZPJMESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM311269 ((S)-1-((2′-(difluoromethyl)-4-methyl-[2,4...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Mississippi | Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra... | J Med Chem 48: 2906-15 (2005) BindingDB Entry DOI: 10.7270/Q2930WGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AP2-associated protein kinase 1 (Homo sapiens (Human)) | BDBM311269 ((S)-1-((2′-(difluoromethyl)-4-methyl-[2,4...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company US Patent | Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra... | US Patent US10155760 (2018) BindingDB Entry DOI: 10.7270/Q2F191S4 | |||||||||||
More data for this Ligand-Target Pair |