BDBM31130 5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11i

SMILES: CCOC(=O)c1c(Cc2ccc(OC)cc2)[nH]c2c1cc(O)c1ccccc21

InChI Key: InChIKey=AHSYATTZSWTSJZ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM31130 (5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11i) Show SMILES CCOC(=O)c1c(Cc2ccc(OC)cc2)[nH]c2c1cc(O)c1ccccc21 Show InChI InChI=1S/C23H21NO4/c1-3-28-23(26)21-18-13-20(25)16-6-4-5-7-17(16)22(18)24-19(21)12-14-8-10-15(27-2)11-9-14/h4-11,13,24-25H,3,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	650	n/a	n/a	7.4	37
Friedrich Alexander University Erlangen					Assay Description For determination of the activity of 5-LO in 40000g supernatant (S40), aliquots of the supernatants were added to reaction mix, and were preincubated...				J Med Chem 52: 3474-83 (2009) Article DOI: 10.1021/jm900212y BindingDB Entry DOI: 10.7270/Q2HM56S5
					More data for this Ligand-Target Pair