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SMILES: CCn1nc(N[C@H](C)CN(C)C)c2ccccc2c1=O

InChI Key: InChIKey=BUQFAKLKNBWLAF-LLVKDONJSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311426   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase KAT2B [719-832]


(Homo sapiens (Human))		BDBM311426
PNG
(US10155764, Example 17A)
Show SMILES CCn1nc(N[C@H](C)CN(C)C)c2ccccc2c1=O |r|
Show InChI InChI=1S/C15H22N4O/c1-5-19-15(20)13-9-7-6-8-12(13)14(17-19)16-11(2)10-18(3)4/h6-9,11H,5,10H2,1-4H3,(H,16,17)/t11-/m1/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
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UniChem
US Patent
n/an/a>5.00E+3n/an/an/an/an/an/a



GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC.

US Patent


Assay Description
His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...

US Patent US10155764 (2018)


BindingDB Entry DOI: 10.7270/Q25M67T9
More data for this
Ligand-Target Pair