BDBM311442 CHEM-US-00139::US10155764, Example 30

SMILES: CN1CCCC1CNc1nn(C)c(=O)c2ccccc12

InChI Key: InChIKey=PVIKXTXNUBMZBU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B [719-832] (Homo sapiens (Human))	BDBM311442 (CHEM-US-00139 | US10155764, Example 30) Show SMILES CN1CCCC1CNc1nn(C)c(=O)c2ccccc12 Show InChI InChI=1S/C15H20N4O/c1-18-9-5-6-11(18)10-16-14-12-7-3-4-8-13(12)15(20)19(2)17-14/h3-4,7-8,11H,5-6,9-10H2,1-2H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				US Patent US10155764 (2018) BindingDB Entry DOI: 10.7270/Q25M67T9
					More data for this Ligand-Target Pair