BDBM311449 CHEM-US-00146::US10155764, Example 35

SMILES: Cn1nc(N[C@@H]2CCCC[C@H]2N)c2ccccc2c1=O

InChI Key: InChIKey=SBYFWRAMNUOMTD-CHWSQXEVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B [719-832] (Homo sapiens (Human))	BDBM311449 (CHEM-US-00146 | US10155764, Example 35) Show SMILES Cn1nc(N[C@@H]2CCCC[C@H]2N)c2ccccc2c1=O |r| Show InChI InChI=1S/C15H20N4O/c1-19-15(20)11-7-3-2-6-10(11)14(18-19)17-13-9-5-4-8-12(13)16/h2-3,6-7,12-13H,4-5,8-9,16H2,1H3,(H,17,18)/t12-,13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				US Patent US10155764 (2018) BindingDB Entry DOI: 10.7270/Q25M67T9
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