BDBM311461 CHEM-US-00158::US10155764, Example 45

SMILES: CN1CCCCC(C1)Nc1nn(C)c(=O)c2ccccc12

InChI Key: InChIKey=FXMWIVFAPJGOOT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B [719-832] (Homo sapiens (Human))	BDBM311461 (CHEM-US-00158 | US10155764, Example 45) Show SMILES CN1CCCCC(C1)Nc1nn(C)c(=O)c2ccccc12 Show InChI InChI=1S/C16H22N4O/c1-19-10-6-5-7-12(11-19)17-15-13-8-3-4-9-14(13)16(21)20(2)18-15/h3-4,8-9,12H,5-7,10-11H2,1-2H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...				US Patent US10155764 (2018) BindingDB Entry DOI: 10.7270/Q25M67T9
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