BDBM31188 thiazol-2-amine, 20

SMILES: CCc1sc(N)nc1-c1ccccc1OC

InChI Key: InChIKey=MPURKHDGUCYKHP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM31188 (thiazol-2-amine, 20) Show SMILES CCc1sc(N)nc1-c1ccccc1OC Show InChI InChI=1S/C12H14N2OS/c1-3-10-11(14-12(13)16-10)8-6-4-5-7-9(8)15-2/h4-7H,3H2,1-2H3,(H2,13,14)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia at Charlottesville					Assay Description His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ...				Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN
					More data for this Ligand-Target Pair
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human))	BDBM31188 (thiazol-2-amine, 20) Show SMILES CCc1sc(N)nc1-c1ccccc1OC Show InChI InChI=1S/C12H14N2OS/c1-3-10-11(14-12(13)16-10)8-6-4-5-7-9(8)15-2/h4-7H,3H2,1-2H3,(H2,13,14)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	7.5	23
University of Virginia at Charlottesville					Assay Description For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c...				Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN
					More data for this Ligand-Target Pair