BDBM31193 thiazol-2-amine, 4
SMILES: Nc1nc2c(ccc3ccccc23)s1
InChI Key: InChIKey=FECQXVPRUCCUIL-UHFFFAOYSA-N
Data: 1 Other
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens (Human)) | BDBM31193 (thiazol-2-amine, 4) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Virginia at Charlottesville | Assay Description For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair |