BDBM31226 2-phenoxybenzoyltryptophan derivative, R5C4

SMILES: Cc1ccc2n(Cc3ccc(OCc4ccccc4)cc3)cc(C[C@H](NC(=O)c3ccccc3Oc3ccccc3)C(O)=O)c2c1

InChI Key: InChIKey=YJHXKFJZIRNVRS-DHUJRADRSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM31226 (2-phenoxybenzoyltryptophan derivative, R5C4) Show SMILES Cc1ccc2n(Cc3ccc(OCc4ccccc4)cc3)cc(C[C@H](NC(=O)c3ccccc3Oc3ccccc3)C(O)=O)c2c1 |r| Show InChI InChI=1S/C39H34N2O5/c1-27-16-21-36-34(22-27)30(25-41(36)24-28-17-19-31(20-18-28)45-26-29-10-4-2-5-11-29)23-35(39(43)44)40-38(42)33-14-8-9-15-37(33)46-32-12-6-3-7-13-32/h2-22,25,35H,23-24,26H2,1H3,(H,40,42)(H,43,44)/t35-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	600	-8.43	n/a	n/a	n/a	n/a	n/a	7.4	23
Schering-Plough Research Institute					Assay Description Ki values were determined from a competition experiment in which serial dilutions of inhibitor were added to compete against a fixed concentration (1...				Anal Biochem 331: 138-46 (2004) Article DOI: 10.1016/j.ab.2004.03.009 BindingDB Entry DOI: 10.7270/Q2VX0DVV
					More data for this Ligand-Target Pair