BDBM312331 2-[3-(4-Methyl-oxazol-2-yl)-4,7-dihydro-5H-thieno[2,3-c]pyran-2-ylcarbamoyl]-cyclopent-1-enecarboxylic acid::US9604977, Example 78

SMILES: Cc1coc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2COCCc12

InChI Key: InChIKey=AVBMIWSWTVKCJE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid-binding protein 5 (FABP5) (Homo sapiens (Human))	BDBM312331 (2-[3-(4-Methyl-oxazol-2-yl)-4,7-dihydro-5H-thieno[...) Show SMILES Cc1coc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2COCCc12 |t:12| Show InChI InChI=1S/C18H18N2O5S/c1-9-7-25-16(19-9)14-12-5-6-24-8-13(12)26-17(14)20-15(21)10-3-2-4-11(10)18(22)23/h7H,2-6,8H2,1H3,(H,20,21)(H,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4) (Homo sapiens (Human))	BDBM312331 (2-[3-(4-Methyl-oxazol-2-yl)-4,7-dihydro-5H-thieno[...) Show SMILES Cc1coc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2COCCc12 |t:12| Show InChI InChI=1S/C18H18N2O5S/c1-9-7-25-16(19-9)14-12-5-6-24-8-13(12)26-17(14)20-15(21)10-3-2-4-11(10)18(22)23/h7H,2-6,8H2,1H3,(H,20,21)(H,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair