BDBM312340 2-[3-(4-Trifluoromethyl-thiazol-2-yl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-cyclohex-1-enecarboxylic acid::US9604977, Example 86

SMILES: OC(=O)C1=C(CCCC1)C(=O)Nc1sc2CCCCc2c1-c1nc(cs1)C(F)(F)F

InChI Key: InChIKey=GOYAHCQRVRZJPP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid-binding protein 5 (FABP5) (Homo sapiens (Human))	BDBM312340 (2-[3-(4-Trifluoromethyl-thiazol-2-yl)-4,5,6,7-tetr...) Show SMILES OC(=O)C1=C(CCCC1)C(=O)Nc1sc2CCCCc2c1-c1nc(cs1)C(F)(F)F |t:3| Show InChI InChI=1S/C20H19F3N2O3S2/c21-20(22,23)14-9-29-17(24-14)15-12-7-3-4-8-13(12)30-18(15)25-16(26)10-5-1-2-6-11(10)19(27)28/h9H,1-8H2,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4) (Homo sapiens (Human))	BDBM312340 (2-[3-(4-Trifluoromethyl-thiazol-2-yl)-4,5,6,7-tetr...) Show SMILES OC(=O)C1=C(CCCC1)C(=O)Nc1sc2CCCCc2c1-c1nc(cs1)C(F)(F)F |t:3| Show InChI InChI=1S/C20H19F3N2O3S2/c21-20(22,23)14-9-29-17(24-14)15-12-7-3-4-8-13(12)30-18(15)25-16(26)10-5-1-2-6-11(10)19(27)28/h9H,1-8H2,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair