BDBM312344 2-[3-(4-Trifluoromethyl-thiazol-2-yl)-4,7-dihydro-5H-thieno[2,3-c]pyran-2-ylcarbamoyl]-cyclohex-1-enecarboxylic acid::US9604977, Example 90

SMILES: OC(=O)C1=C(CCCC1)C(=O)Nc1sc2COCCc2c1-c1nc(cs1)C(F)(F)F

InChI Key: InChIKey=VFGQKHNIOXNFLW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid-binding protein 5 (FABP5) (Homo sapiens (Human))	BDBM312344 (2-[3-(4-Trifluoromethyl-thiazol-2-yl)-4,7-dihydro-...) Show SMILES OC(=O)C1=C(CCCC1)C(=O)Nc1sc2COCCc2c1-c1nc(cs1)C(F)(F)F |t:3| Show InChI InChI=1S/C19H17F3N2O4S2/c20-19(21,22)13-8-29-16(23-13)14-11-5-6-28-7-12(11)30-17(14)24-15(25)9-3-1-2-4-10(9)18(26)27/h8H,1-7H2,(H,24,25)(H,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4) (Homo sapiens (Human))	BDBM312344 (2-[3-(4-Trifluoromethyl-thiazol-2-yl)-4,7-dihydro-...) Show SMILES OC(=O)C1=C(CCCC1)C(=O)Nc1sc2COCCc2c1-c1nc(cs1)C(F)(F)F |t:3| Show InChI InChI=1S/C19H17F3N2O4S2/c20-19(21,22)13-8-29-16(23-13)14-11-5-6-28-7-12(11)30-17(14)24-15(25)9-3-1-2-4-10(9)18(26)27/h8H,1-7H2,(H,24,25)(H,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair