BDBM312404 2-[6,6-Difluoro-3-(4-methyl-thiazol-2-yl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl-carbamoyl]-cyclopent-1-enecarboxylic acid::US9604977, Example 150

SMILES: Cc1csc(n1)-c1c2CCC(F)(F)Cc2sc1NC(=O)C1=C(CCC1)C(O)=O

InChI Key: InChIKey=LVMJRELONBOYJX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid-binding protein 5 (FABP5) (Homo sapiens (Human))	BDBM312404 (2-[6,6-Difluoro-3-(4-methyl-thiazol-2-yl)-4,5,6,7-...) Show SMILES Cc1csc(n1)-c1c2CCC(F)(F)Cc2sc1NC(=O)C1=C(CCC1)C(O)=O |t:23| Show InChI InChI=1S/C19H18F2N2O3S2/c1-9-8-27-16(22-9)14-12-5-6-19(20,21)7-13(12)28-17(14)23-15(24)10-3-2-4-11(10)18(25)26/h8H,2-7H2,1H3,(H,23,24)(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4) (Homo sapiens (Human))	BDBM312404 (2-[6,6-Difluoro-3-(4-methyl-thiazol-2-yl)-4,5,6,7-...) Show SMILES Cc1csc(n1)-c1c2CCC(F)(F)Cc2sc1NC(=O)C1=C(CCC1)C(O)=O |t:23| Show InChI InChI=1S/C19H18F2N2O3S2/c1-9-8-27-16(22-9)14-12-5-6-19(20,21)7-13(12)28-17(14)23-15(24)10-3-2-4-11(10)18(25)26/h8H,2-7H2,1H3,(H,23,24)(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair