BDBM312485 2-[6,6-Difluoro-3-(4-isopropyl-thiazol-2-yl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-cyclopent-1-enecarboxylic acid::US9604977, Example 231

SMILES: CC(C)c1csc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CC(F)(F)CCc12

InChI Key: InChIKey=CAMRJQYQDWSOQP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312485   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid-binding protein 5 (FABP5) (Homo sapiens (Human))	BDBM312485 (2-[6,6-Difluoro-3-(4-isopropyl-thiazol-2-yl)-4,5,6...) Show SMILES CC(C)c1csc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CC(F)(F)CCc12 |t:14| Show InChI InChI=1S/C21H22F2N2O3S2/c1-10(2)14-9-29-18(24-14)16-13-6-7-21(22,23)8-15(13)30-19(16)25-17(26)11-4-3-5-12(11)20(27)28/h9-10H,3-8H2,1-2H3,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4) (Homo sapiens (Human))	BDBM312485 (2-[6,6-Difluoro-3-(4-isopropyl-thiazol-2-yl)-4,5,6...) Show SMILES CC(C)c1csc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CC(F)(F)CCc12 |t:14| Show InChI InChI=1S/C21H22F2N2O3S2/c1-10(2)14-9-29-18(24-14)16-13-6-7-21(22,23)8-15(13)30-19(16)25-17(26)11-4-3-5-12(11)20(27)28/h9-10H,3-8H2,1-2H3,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair