BDBM312490 2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-5,5-dimethyl-4,5,6,7-tetrahydro-benzo[b]thiophen-2-ylcarbamoyl]-cyclopent-1-enecarboxylic acid::US9604977, Example 236
SMILES: CC1(C)CCc2sc(NC(=O)C3=C(CCC3)C(O)=O)c(-c3nc(no3)C3CC3)c2C1
InChI Key: InChIKey=RLEBTWMSJBDSFI-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty acid-binding protein 5 (FABP5) (Homo sapiens (Human)) | BDBM312490 (2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-5,5-dim...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffman-La Roche Inc. US Patent | Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra... | US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid-binding protein 4 (FABP4) (Homo sapiens (Human)) | BDBM312490 (2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-5,5-dim...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Hoffman-La Roche Inc. US Patent | Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra... | US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB | |||||||||||
More data for this Ligand-Target Pair |