BDBM312510 (R)-1-[[3-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl]carbamoyl]pyrrolidine-2-carboxylic acid::US9604977, Example 256

SMILES: OC(=O)[C@H]1CCCN1C(=O)Nc1sc2CCCCCc2c1-c1nc(no1)C(F)(F)F

InChI Key: InChIKey=OJMIJXSYZBEDDN-SNVBAGLBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid-binding protein 5 (FABP5) (Homo sapiens (Human))	BDBM312510 ((R)-1-[[3-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-y...) Show SMILES OC(=O)[C@H]1CCCN1C(=O)Nc1sc2CCCCCc2c1-c1nc(no1)C(F)(F)F |r| Show InChI InChI=1S/C18H19F3N4O4S/c19-18(20,21)16-22-13(29-24-16)12-9-5-2-1-3-7-11(9)30-14(12)23-17(28)25-8-4-6-10(25)15(26)27/h10H,1-8H2,(H,23,28)(H,26,27)/t10-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair
Fatty acid-binding protein 4 (FABP4) (Homo sapiens (Human))	BDBM312510 ((R)-1-[[3-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-y...) Show SMILES OC(=O)[C@H]1CCCN1C(=O)Nc1sc2CCCCCc2c1-c1nc(no1)C(F)(F)F |r| Show InChI InChI=1S/C18H19F3N4O4S/c19-18(20,21)16-22-13(29-24-16)12-9-5-2-1-3-7-11(9)30-14(12)23-17(28)25-8-4-6-10(25)15(26)27/h10H,1-8H2,(H,23,28)(H,26,27)/t10-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...				US Patent US9604977 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CJB
					More data for this Ligand-Target Pair