null

SMILES: COc1ccn2c(nc(-c3cccc(c3)C#C[C@@](C)(O)c3nnc(C)o3)c2c1)C(N)=O

InChI Key: InChIKey=FBPFFRUKCCRXMB-JOCHJYFZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM312891 (1-[3-[(3R)-3-hydroxy-3-(5- methyl-1,3,4-oxadiazol-...) Show SMILES COc1ccn2c(nc(-c3cccc(c3)C#C[C@@](C)(O)c3nnc(C)o3)c2c1)C(N)=O |r| Show InChI InChI=1S/C22H19N5O4/c1-13-25-26-21(31-13)22(2,29)9-7-14-5-4-6-15(11-14)18-17-12-16(30-3)8-10-27(17)20(24-18)19(23)28/h4-6,8,10-12,29H,1-3H3,(H2,23,28)/t22-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...				US Patent US9605005 (2017) BindingDB Entry DOI: 10.7270/Q2T43W61
					More data for this Ligand-Target Pair