BDBM314129 3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic acid::US10179769, Example 33::US10807956, Example 33::US9611221, Example 33::US9725441, Example 33::US9828343, Example 33

SMILES: OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1

InChI Key: InChIKey=WCZTUVDGEDXPNK-UHFFFAOYSA-N

Data: 15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 314129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...				US Patent US9611221 (2017) BindingDB Entry DOI: 10.7270/Q26975NT
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US9611221 (2017) BindingDB Entry DOI: 10.7270/Q26975NT
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...				US Patent US9725441 (2017) BindingDB Entry DOI: 10.7270/Q29Z971T
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...				US Patent US9725441 (2017) BindingDB Entry DOI: 10.7270/Q29Z971T
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US9725441 (2017) BindingDB Entry DOI: 10.7270/Q29Z971T
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...				US Patent US10179769 (2019) BindingDB Entry DOI: 10.7270/Q2J38VPZ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...				US Patent US10179769 (2019) BindingDB Entry DOI: 10.7270/Q2J38VPZ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10179769 (2019) BindingDB Entry DOI: 10.7270/Q2J38VPZ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description Jarid1A Assay: The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ab...				US Patent US9828343 (2017) BindingDB Entry DOI: 10.7270/Q2ST7S40
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description Jarid1B: The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction condit...				US Patent US9828343 (2017) BindingDB Entry DOI: 10.7270/Q2ST7S40
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description JMJD2C: The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditio...				US Patent US9828343 (2017) BindingDB Entry DOI: 10.7270/Q2ST7S40
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...				US Patent US10807956 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384 well plate format under the following reaction conditions: 0.8...				US Patent US10807956 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10807956 (2020)
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM314129 (3-[(2-phenoxybenzyl)amino]pyridine-4-carboxylic ac...) Show SMILES OC(=O)c1ccncc1NCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C19H16N2O3/c22-19(23)16-10-11-20-13-17(16)21-12-14-6-4-5-9-18(14)24-15-7-2-1-3-8-15/h1-11,13,21H,12H2,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...				US Patent US9611221 (2017) BindingDB Entry DOI: 10.7270/Q26975NT
					More data for this Ligand-Target Pair