BDBM314401 US9611249, Compound 32::{4-[({[5-(propan-2-yl)-1H-indazol-3-yl] carbonyl}amino)methyl]piperidin-1-yl} acetic acid

SMILES: CC(C)c1ccc2[nH]nc(C(=O)NCC3CCN(CC(O)=O)CC3)c2c1

InChI Key: InChIKey=BLIIBYBMFHPLET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM314401 (US9611249, Compound 32 | {4-[({[5-(propan-2-yl)-1H...) Show SMILES CC(C)c1ccc2[nH]nc(C(=O)NCC3CCN(CC(O)=O)CC3)c2c1 Show InChI InChI=1S/C19H26N4O3/c1-12(2)14-3-4-16-15(9-14)18(22-21-16)19(26)20-10-13-5-7-23(8-6-13)11-17(24)25/h3-4,9,12-13H,5-8,10-11H2,1-2H3,(H,20,26)(H,21,22)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. US Patent					Assay Description Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...				US Patent US9611249 (2017) BindingDB Entry DOI: 10.7270/Q2JH3P79
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