BDBM314403 US9611249, Compound 34::[4-({[(5-cyclohexyl-1H-indazol-3-yl) carbonyl]amino}methyl)piperidin-1-yl] acetic acid

SMILES: OC(=O)CN1CCC(CNC(=O)c2n[nH]c3ccc(cc23)C2CCCCC2)CC1

InChI Key: InChIKey=BGMLEHXLZHSVAW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM314403 (US9611249, Compound 34 | [4-({[(5-cyclohexyl-1H-in...) Show SMILES OC(=O)CN1CCC(CNC(=O)c2n[nH]c3ccc(cc23)C2CCCCC2)CC1 Show InChI InChI=1S/C22H30N4O3/c27-20(28)14-26-10-8-15(9-11-26)13-23-22(29)21-18-12-17(6-7-19(18)24-25-21)16-4-2-1-3-5-16/h6-7,12,15-16H,1-5,8-11,13-14H2,(H,23,29)(H,24,25)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. US Patent					Assay Description Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...				US Patent US9611249 (2017) BindingDB Entry DOI: 10.7270/Q2JH3P79
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