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SMILES: CCCCCc1ccc2[nH]nc(C(=O)NCC3CCN(CC(O)=O)CC3)c2c1

InChI Key: InChIKey=DFDLZTUVRIFWRO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 314404   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))		BDBM314404
PNG
(US9611249, Compound 35 | [4-({[(5-pentyl-1H-indazo...)
Show SMILES CCCCCc1ccc2[nH]nc(C(=O)NCC3CCN(CC(O)=O)CC3)c2c1
Show InChI InChI=1S/C21H30N4O3/c1-2-3-4-5-15-6-7-18-17(12-15)20(24-23-18)21(28)22-13-16-8-10-25(11-9-16)14-19(26)27/h6-7,12,16H,2-5,8-11,13-14H2,1H3,(H,22,28)(H,23,24)(H,26,27)
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US Patent
n/an/a 2.04E+3n/an/an/an/an/an/a



AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.

US Patent


Assay Description
Activity on human GSK-3β was assessed using the following methods (according to Meijer et al., Chem. Biol., 2003-10:1255-1266).In a first screen...

US Patent US9611249 (2017)


BindingDB Entry DOI: 10.7270/Q2JH3P79
More data for this
Ligand-Target Pair