BDBM3154 2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]bicyclo[2.2.1]heptan-2-yl}oxy)carbonyl]phenyl}carbonyl)-3-hydroxybenzoic acid::Balanol analog 20::Balanol analog 21
SMILES: OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OC1C2CCC(C2)C1NC(=O)c1ccc(O)cc1
InChI Key: InChIKey=GQCWIZZVARXZGR-UHFFFAOYSA-N
Data: 19 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 55 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-dependent protein kinase (PKA) (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description Inhibition of Protein kinase C beta 2 | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PKC alpha and beta-2 (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 45 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PKC alpha and beta-2 (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PKC alpha and beta-2 (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 30 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PKC alpha and beta-2 (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C, gamma (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C, gamma (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C delta type (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C, epsilon (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C, epsilon (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C, eta (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C, eta (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C (PKC) (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C (PKC) (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories | Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM3154 (2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Sphinx Laboratories | Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. | Bioorg Med Chem Lett 5: 2211-6 (1995) Article DOI: 10.1016/0960-894X(95)00382-4 BindingDB Entry DOI: 10.7270/Q2QR4V9M | |||||||||||
More data for this Ligand-Target Pair |