BDBM315481 US10172858, Table 1.5

SMILES: Nc1nc2cc(ccc2o1)-c1nn(C2CCOCC2)c2ncnc(N)c12

InChI Key: InChIKey=DSPUBRSXSQDQMB-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 315481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM315481 (US10172858, Table 1.5) Show SMILES Nc1nc2cc(ccc2o1)-c1nn(C2CCOCC2)c2ncnc(N)c12 Show InChI InChI=1S/C17H17N7O2/c18-15-13-14(9-1-2-12-11(7-9)22-17(19)26-12)23-24(16(13)21-8-20-15)10-3-5-25-6-4-10/h1-2,7-8,10H,3-6H2,(H2,19,22)(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
INTELLIKINE LLC US Patent					Assay Description This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...				US Patent US10172858 (2019) BindingDB Entry DOI: 10.7270/Q2736T01
					More data for this Ligand-Target Pair
PI3-kinase class I (Homo sapiens (Human))	BDBM315481 (US10172858, Table 1.5) Show SMILES Nc1nc2cc(ccc2o1)-c1nn(C2CCOCC2)c2ncnc(N)c12 Show InChI InChI=1S/C17H17N7O2/c18-15-13-14(9-1-2-12-11(7-9)22-17(19)26-12)23-24(16(13)21-8-20-15)10-3-5-25-6-4-10/h1-2,7-8,10H,3-6H2,(H2,19,22)(H2,18,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
INTELLIKINE LLC US Patent					Assay Description This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...				US Patent US10172858 (2019) BindingDB Entry DOI: 10.7270/Q2736T01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM315481 (US10172858, Table 1.5) Show SMILES Nc1nc2cc(ccc2o1)-c1nn(C2CCOCC2)c2ncnc(N)c12 Show InChI InChI=1S/C17H17N7O2/c18-15-13-14(9-1-2-12-11(7-9)22-17(19)26-12)23-24(16(13)21-8-20-15)10-3-5-25-6-4-10/h1-2,7-8,10H,3-6H2,(H2,19,22)(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
INTELLIKINE LLC US Patent					Assay Description This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...				US Patent US10172858 (2019) BindingDB Entry DOI: 10.7270/Q2736T01
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM315481 (US10172858, Table 1.5) Show SMILES Nc1nc2cc(ccc2o1)-c1nn(C2CCOCC2)c2ncnc(N)c12 Show InChI InChI=1S/C17H17N7O2/c18-15-13-14(9-1-2-12-11(7-9)22-17(19)26-12)23-24(16(13)21-8-20-15)10-3-5-25-6-4-10/h1-2,7-8,10H,3-6H2,(H2,19,22)(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
INTELLIKINE LLC US Patent					Assay Description This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...				US Patent US10172858 (2019) BindingDB Entry DOI: 10.7270/Q2736T01
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human))	BDBM315481 (US10172858, Table 1.5) Show SMILES Nc1nc2cc(ccc2o1)-c1nn(C2CCOCC2)c2ncnc(N)c12 Show InChI InChI=1S/C17H17N7O2/c18-15-13-14(9-1-2-12-11(7-9)22-17(19)26-12)23-24(16(13)21-8-20-15)10-3-5-25-6-4-10/h1-2,7-8,10H,3-6H2,(H2,19,22)(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INTELLIKINE LLC US Patent					Assay Description This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...				US Patent US10172858 (2019) BindingDB Entry DOI: 10.7270/Q2736T01
					More data for this Ligand-Target Pair