BDBM316092 US9616064, Compound 24c

SMILES: Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCCc1ccccc1

InChI Key: InChIKey=NDMKTJWCSWYAME-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM316092 (US9616064, Compound 24c) Show SMILES Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C21H19N5O/c22-21-24-13-10-19(25-21)26-14-11-16-17(7-4-8-18(16)26)20(27)23-12-9-15-5-2-1-3-6-15/h1-8,10-11,13-14H,9,12H2,(H,23,27)(H2,22,24,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent									US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM316092 (US9616064, Compound 24c) Show SMILES Nc1nccc(n1)-n1ccc2c(cccc12)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C21H19N5O/c22-21-24-13-10-19(25-21)26-14-11-16-17(7-4-8-18(16)26)20(27)23-12-9-15-5-2-1-3-6-15/h1-8,10-11,13-14H,9,12H2,(H,23,27)(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. US Patent					Assay Description The inventors undertook a screen of the NCI Diversity set using a Z-lyte FRET assay (Kang et al. (2009); Wu et al. (2010)) to measure kinase inhibiti...				US Patent US9616064 (2017) BindingDB Entry DOI: 10.7270/Q2KD2106
					More data for this Ligand-Target Pair