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SMILES: COC(=O)c1cc(Nc2cc(ncn2)-c2ccccc2OC)ccc1O

InChI Key: InChIKey=MGJXIKGWPXNMEB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-T1/Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM316193 (US10294218, Example 21 | US9617225, Example 21 | m...) Show SMILES COC(=O)c1cc(Nc2cc(ncn2)-c2ccccc2OC)ccc1O Show InChI InChI=1S/C19H17N3O4/c1-25-17-6-4-3-5-13(17)15-10-18(21-11-20-15)22-12-7-8-16(23)14(9-12)19(24)26-2/h3-11,23H,1-2H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				Bioorg Med Chem Lett 18: 1022-6 (2008) BindingDB Entry DOI: 10.7270/Q2RB76X4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM316193 (US10294218, Example 21 | US9617225, Example 21 | m...) Show SMILES COC(=O)c1cc(Nc2cc(ncn2)-c2ccccc2OC)ccc1O Show InChI InChI=1S/C19H17N3O4/c1-25-17-6-4-3-5-13(17)15-10-18(21-11-20-15)22-12-7-8-16(23)14(9-12)19(24)26-2/h3-11,23H,1-2H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
VIROSTATICS SRL US Patent					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				US Patent US9617225 (2017) BindingDB Entry DOI: 10.7270/Q29W0HK6
					More data for this Ligand-Target Pair