BDBM316211 N-(3-((1H-benzo[d]imidazol-1-yl)methyl)-4-ethoxyphenyl)-6-(2-methoxyphenyl)pyrimidin-4-amine::US10294218, Example 39::US9617225, Example 39

SMILES: CCOc1ccc(Nc2cc(ncn2)-c2ccccc2OC)cc1Cn1cnc2ccccc12

InChI Key: InChIKey=JWXKFKUHLAQGQX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 316211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 9 (CDK9) (Homo sapiens (Human))	BDBM316211 (N-(3-((1H-benzo[d]imidazol-1-yl)methyl)-4-ethoxyph...) Show SMILES CCOc1ccc(Nc2cc(ncn2)-c2ccccc2OC)cc1Cn1cnc2ccccc12 Show InChI InChI=1S/C27H25N5O2/c1-3-34-25-13-12-20(14-19(25)16-32-18-30-22-9-5-6-10-24(22)32)31-27-15-23(28-17-29-27)21-8-4-7-11-26(21)33-2/h4-15,17-18H,3,16H2,1-2H3,(H,28,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				Bioorg Med Chem Lett 18: 1022-6 (2008) BindingDB Entry DOI: 10.7270/Q2RB76X4
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM316211 (N-(3-((1H-benzo[d]imidazol-1-yl)methyl)-4-ethoxyph...) Show SMILES CCOc1ccc(Nc2cc(ncn2)-c2ccccc2OC)cc1Cn1cnc2ccccc12 Show InChI InChI=1S/C27H25N5O2/c1-3-34-25-13-12-20(14-19(25)16-32-18-30-22-9-5-6-10-24(22)32)31-27-15-23(28-17-29-27)21-8-4-7-11-26(21)33-2/h4-15,17-18H,3,16H2,1-2H3,(H,28,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
VIROSTATICS SRL US Patent					Assay Description The activity of the compounds described in the present invention can be determined by measuring the phosphorylation of a fluorescently-labeled peptid...				US Patent US9617225 (2017) BindingDB Entry DOI: 10.7270/Q29W0HK6
					More data for this Ligand-Target Pair