BDBM316374 US9617239, BRITE-355417

SMILES: Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccccc1Br

InChI Key: InChIKey=GFHGTKCVSNHYRZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-glucuronidase (Homo sapiens (Human))	BDBM316374 (US9617239, BRITE-355417) Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccccc1Br Show InChI InChI=1S/C21H21BrClN3O3S2/c22-18-7-2-1-4-15(18)14-25-31(27,28)20-13-19(23)21(30-20)29-17-6-3-5-16(12-17)26-10-8-24-9-11-26/h1-7,12-13,24-25H,8-11,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair