BindingDB logo
myBDB logout

null

SMILES: O=c1[nH]c(NCc2ccc3OCOc3c2)nc2n(ncc12)C1CCCC1

InChI Key: InChIKey=CMOYKYVJWNDOIK-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317082   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A


(Homo sapiens (Human))		BDBM317082
PNG
(US9617269, Compound WYQ-33)
Show SMILES O=c1[nH]c(NCc2ccc3OCOc3c2)nc2n(ncc12)C1CCCC1
Show InChI InChI=1S/C18H19N5O3/c24-17-13-9-20-23(12-3-1-2-4-12)16(13)21-18(22-17)19-8-11-5-6-14-15(7-11)26-10-25-14/h5-7,9,12H,1-4,8,10H2,(H2,19,21,22,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 29n/an/an/an/an/an/a



Sun Yat-Sen University; University of North Carolina at Chapel Hill

US Patent


Assay Description
Inhibition activities of all the N-substituted pyrazolo [3,4-d] pyrimidine ketone compounds according to the present invention to the phosphodiestera...

US Patent US9617269 (2017)


BindingDB Entry DOI: 10.7270/Q2RX9F4B
More data for this
Ligand-Target Pair