BDBM31743 8-(2-carbethoxyphenoxy)carbonyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid::8-(2-ethoxycarbonylphenoxy)carbonyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid::8-[(2-ethoxycarbonylphenoxy)-oxomethyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid::MLS-0091957.0001::cid_2925672

SMILES: CCOC(=O)c1ccccc1OC(=O)c1ccc2NC(C3CC=CC3c2c1)C(O)=O

InChI Key: InChIKey=UVOIZGYJDKPXFY-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 31743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MKP-3 (Rattus norvegicus)	BDBM31743 (8-(2-carbethoxyphenoxy)carbonyl-3a,4,5,9b-tetrahyd...) Show SMILES CCOC(=O)c1ccccc1OC(=O)c1ccc2NC(C3CC=CC3c2c1)C(O)=O |c:23| Show InChI InChI=1S/C23H21NO6/c1-2-29-23(28)16-6-3-4-9-19(16)30-22(27)13-10-11-18-17(12-13)14-7-5-8-15(14)20(24-18)21(25)26/h3-7,9-12,14-15,20,24H,2,8H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	7.0	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: NIH...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2N87841
					More data for this Ligand-Target Pair
MKP-3 (Rattus norvegicus)	BDBM31743 (8-(2-carbethoxyphenoxy)carbonyl-3a,4,5,9b-tetrahyd...) Show SMILES CCOC(=O)c1ccccc1OC(=O)c1ccc2NC(C3CC=CC3c2c1)C(O)=O |c:23| Show InChI InChI=1S/C23H21NO6/c1-2-29-23(28)16-6-3-4-9-19(16)30-22(27)13-10-11-18-17(12-13)14-7-5-8-15(14)20(24-18)21(25)26/h3-7,9-12,14-15,20,24H,2,8H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q25H7DPX
					More data for this Ligand-Target Pair
heat shock 70kDa protein 8 isoform 2 (Homo sapiens (Human))	BDBM31743 (8-(2-carbethoxyphenoxy)carbonyl-3a,4,5,9b-tetrahyd...) Show SMILES CCOC(=O)c1ccccc1OC(=O)c1ccc2NC(C3CC=CC3c2c1)C(O)=O |c:23| Show InChI InChI=1S/C23H21NO6/c1-2-29-23(28)16-6-3-4-9-19(16)30-22(27)13-10-11-18-17(12-13)14-7-5-8-15(14)20(24-18)21(25)26/h3-7,9-12,14-15,20,24H,2,8H2,1H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q20G3HKD
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM31743 (8-(2-carbethoxyphenoxy)carbonyl-3a,4,5,9b-tetrahyd...) Show SMILES CCOC(=O)c1ccccc1OC(=O)c1ccc2NC(C3CC=CC3c2c1)C(O)=O |c:23| Show InChI InChI=1S/C23H21NO6/c1-2-29-23(28)16-6-3-4-9-19(16)30-22(27)13-10-11-18-17(12-13)14-7-5-8-15(14)20(24-18)21(25)26/h3-7,9-12,14-15,20,24H,2,8H2,1H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2474894
					More data for this Ligand-Target Pair
Heat Shock 70kDa Protein 1 (Homo sapiens (Human))	BDBM31743 (8-(2-carbethoxyphenoxy)carbonyl-3a,4,5,9b-tetrahyd...) Show SMILES CCOC(=O)c1ccccc1OC(=O)c1ccc2NC(C3CC=CC3c2c1)C(O)=O |c:23| Show InChI InChI=1S/C23H21NO6/c1-2-29-23(28)16-6-3-4-9-19(16)30-22(27)13-10-11-18-17(12-13)14-7-5-8-15(14)20(24-18)21(25)26/h3-7,9-12,14-15,20,24H,2,8H2,1H3,(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	3.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2S75DRW
					More data for this Ligand-Target Pair