null

SMILES: COc1cc(ccc1Nc1nc(OC2CCC2)c2c(c[nH]c2n1)-c1ccc2nc(C)oc2c1)C(=O)NC1COC1

InChI Key: InChIKey=KXMLNXWIFJZEJN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 317481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase TTK (Homo sapiens (Human))	BDBM317481 (4-(4-cyclobutoxy-5-(2- methylbenzo[d]oxazol-6-yl)-...) Show SMILES COc1cc(ccc1Nc1nc(OC2CCC2)c2c(c[nH]c2n1)-c1ccc2nc(C)oc2c1)C(=O)NC1COC1 Show InChI InChI=1S/C29H28N6O5/c1-15-31-22-8-6-16(10-24(22)39-15)20-12-30-26-25(20)28(40-19-4-3-5-19)35-29(34-26)33-21-9-7-17(11-23(21)37-2)27(36)32-18-13-38-14-18/h6-12,18-19H,3-5,13-14H2,1-2H3,(H,32,36)(H2,30,33,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, LLC US Patent					Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...				US Patent US9623028 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34R8
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK2 (Homo sapiens (Human))	BDBM317481 (4-(4-cyclobutoxy-5-(2- methylbenzo[d]oxazol-6-yl)-...) Show SMILES COc1cc(ccc1Nc1nc(OC2CCC2)c2c(c[nH]c2n1)-c1ccc2nc(C)oc2c1)C(=O)NC1COC1 Show InChI InChI=1S/C29H28N6O5/c1-15-31-22-8-6-16(10-24(22)39-15)20-12-30-26-25(20)28(40-19-4-3-5-19)35-29(34-26)33-21-9-7-17(11-23(21)37-2)27(36)32-18-13-38-14-18/h6-12,18-19H,3-5,13-14H2,1-2H3,(H,32,36)(H2,30,33,34,35)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.92	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, LLC US Patent					Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...				US Patent US9623028 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34R8
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM317481 (4-(4-cyclobutoxy-5-(2- methylbenzo[d]oxazol-6-yl)-...) Show SMILES COc1cc(ccc1Nc1nc(OC2CCC2)c2c(c[nH]c2n1)-c1ccc2nc(C)oc2c1)C(=O)NC1COC1 Show InChI InChI=1S/C29H28N6O5/c1-15-31-22-8-6-16(10-24(22)39-15)20-12-30-26-25(20)28(40-19-4-3-5-19)35-29(34-26)33-21-9-7-17(11-23(21)37-2)27(36)32-18-13-38-14-18/h6-12,18-19H,3-5,13-14H2,1-2H3,(H,32,36)(H2,30,33,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	526	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, LLC US Patent					Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet...				US Patent US9623028 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34R8
					More data for this Ligand-Target Pair