BDBM31765 MLS-0024020.0001::N-(5-methyl-1,2-oxazol-3-yl)-2-thiophen-2-yl-ethanamide::N-(5-methyl-1,2-oxazol-3-yl)-2-thiophen-2-ylacetamide::N-(5-methyl-3-isoxazolyl)-2-thiophen-2-ylacetamide::N-(5-methylisoxazol-3-yl)-2-(2-thienyl)acetamide::cid_717599

SMILES: Cc1cc(NC(=O)Cc2cccs2)no1

InChI Key: InChIKey=OPYMOTLKQFPQGP-UHFFFAOYSA-N

Data: 13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 31765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MKP-3 (Rattus norvegicus)	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	7.0	23
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Burnham Center for Chemical Genomics (BCCG) Source Affiliation: Burnham Institute for Medical Research (BIMR, La Jolla, CA) Network: NIH...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2N87841
					More data for this Ligand-Target Pair
MKP-3 (Rattus norvegicus)	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q25H7DPX
					More data for this Ligand-Target Pair
Glyceraldehyde-3-phosphate dehydrogenase liver (Homo sapiens (Human))	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	9.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q289148T
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2GX48ZN
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2474894
					More data for this Ligand-Target Pair
PTK2B protein tyrosine kinase 2 beta (PTK2B) (Homo sapiens (Human))	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	6.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2H993M3
					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Tryapanosom cruzi cruzain by quantitative high throughput screening				J Med Chem 53: 37-51 (2010) Article DOI: 10.1021/jm901070c BindingDB Entry DOI: 10.7270/Q2ZP466W
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2RJ4GWX
					More data for this Ligand-Target Pair
BZLF2 (Human herpesvirus 4 type 2)	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2057DCW
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	4.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2J67FCM
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	5.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DF6PNW
					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Tryapanosom cruzi cruzain by Flexstation microplate spectrofluorometry				J Med Chem 53: 37-51 (2010) Article DOI: 10.1021/jm901070c BindingDB Entry DOI: 10.7270/Q2ZP466W
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM31765 (MLS-0024020.0001 | N-(5-methyl-1,2-oxazol-3-yl)-2-...) Show SMILES Cc1cc(NC(=O)Cc2cccs2)no1 Show InChI InChI=1S/C10H10N2O2S/c1-7-5-9(12-14-7)11-10(13)6-8-3-2-4-15-8/h2-5H,6H2,1H3,(H,11,12,13)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23X8539
					More data for this Ligand-Target Pair