BDBM318948 2-Methyl-2-[[7-(4-nitrophenyl)benzo[d]isothiazol-6-yl]thio]propanoic acid::US10173990, Example 72

SMILES: CC(C)(Sc1ccc2cnsc2c1-c1ccc(cc1)[N+]([O-])=O)C(O)=O

InChI Key: InChIKey=FOXTUGSWQSXURA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 318948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 12 (Homo sapiens (Human))	BDBM318948 (2-Methyl-2-[[7-(4-nitrophenyl)benzo[d]isothiazol-6...) Show SMILES CC(C)(Sc1ccc2cnsc2c1-c1ccc(cc1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C17H14N2O4S2/c1-17(2,16(20)21)24-13-8-5-11-9-18-25-15(11)14(13)10-3-6-12(7-4-10)19(22)23/h3-9H,1-2H3,(H,20,21)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc. US Patent					Assay Description URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...				US Patent US10173990 (2019) BindingDB Entry DOI: 10.7270/Q2RR21BP
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