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SMILES: FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1C(F)(F)F

InChI Key: InChIKey=KATKBFOVCFHOIA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 319604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 2B (Homo sapiens (Human))	BDBM319604 (2-[1-[[2-chloro-3- (trifluoromethyl)phenyl]methyl]...) Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1C(F)(F)F Show InChI InChI=1S/C19H12F6N6/c20-18(21,22)13-3-1-2-12(17(13)19(23,24)25)8-31-9-16(27-10-31)14-6-11(4-5-26-14)15-7-28-30-29-15/h1-7,9-10H,8H2,(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair
Histone lysine demethylase PHF8 (Homo sapiens (Human))	BDBM319604 (2-[1-[[2-chloro-3- (trifluoromethyl)phenyl]methyl]...) Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1C(F)(F)F Show InChI InChI=1S/C19H12F6N6/c20-18(21,22)13-3-1-2-12(17(13)19(23,24)25)8-31-9-16(27-10-31)14-6-11(4-5-26-14)15-7-28-30-29-15/h1-7,9-10H,8H2,(H,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2A (Homo sapiens (Human))	BDBM319604 (2-[1-[[2-chloro-3- (trifluoromethyl)phenyl]methyl]...) Show SMILES FC(F)(F)c1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1C(F)(F)F Show InChI InChI=1S/C19H12F6N6/c20-18(21,22)13-3-1-2-12(17(13)19(23,24)25)8-31-9-16(27-10-31)14-6-11(4-5-26-14)15-7-28-30-29-15/h1-7,9-10H,8H2,(H,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of FBXL11 was determined in 384-well plate format under the following reaction conditions: 0.15...				US Patent US10174003 (2019) BindingDB Entry DOI: 10.7270/Q2417053
					More data for this Ligand-Target Pair