BDBM319754 7-(4-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)butyl)-3,4-dihydroquinolin-2(1H)-one::US10174011, Example 22

SMILES: O=C1CCc2ccc(CCCCN3CCN(CC3)c3cccc4sccc34)cc2N1

InChI Key: InChIKey=DVWFBFACSVVQQZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319754   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM319754 (7-(4-(4-(benzo[b]thiophen-4-yl)piperazin-1-yl)buty...) Show SMILES O=C1CCc2ccc(CCCCN3CCN(CC3)c3cccc4sccc34)cc2N1 Show InChI InChI=1S/C25H29N3OS/c29-25-10-9-20-8-7-19(18-22(20)26-25)4-1-2-12-27-13-15-28(16-14-27)23-5-3-6-24-21(23)11-17-30-24/h3,5-8,11,17-18H,1-2,4,9-10,12-16H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.16	n/a	n/a	n/a	n/a	n/a	n/a
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES; SUZHOU VIGONVITA LIFE SCIENCES CO., LTD.; TOPHARMAN SHANDONG CO., LTD. US Patent					Assay Description The D2 receptor agonism activity test (The agonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293 cells...				US Patent US10174011 (2019) BindingDB Entry DOI: 10.7270/Q2VH5QX7
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