null

SMILES: Cc1cnc(s1)-c1cc(Oc2ccnc(C)c2)cc(c1)C(=O)NCc1ccc(C)nn1

InChI Key: InChIKey=XCSQCNBYINKWNK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 319934   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM319934 (N-[(6- Methyl- pyridazin-3- yl)methyl]-3- [(2- met...) Show SMILES Cc1cnc(s1)-c1cc(Oc2ccnc(C)c2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H21N5O2S/c1-14-4-5-19(28-27-14)13-25-22(29)17-9-18(23-26-12-16(3)31-23)11-21(10-17)30-20-6-7-24-15(2)8-20/h4-12H,13H2,1-3H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10183937 (2019) BindingDB Entry DOI: 10.7270/Q2028TNS
					More data for this Ligand-Target Pair
P2X purinoceptor 2 (Homo sapiens (Human))	BDBM319934 (N-[(6- Methyl- pyridazin-3- yl)methyl]-3- [(2- met...) Show SMILES Cc1cnc(s1)-c1cc(Oc2ccnc(C)c2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H21N5O2S/c1-14-4-5-19(28-27-14)13-25-22(29)17-9-18(23-26-12-16(3)31-23)11-21(10-17)30-20-6-7-24-15(2)8-20/h4-12H,13H2,1-3H3,(H,25,29)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10183937 (2019) BindingDB Entry DOI: 10.7270/Q2028TNS
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM319934 (N-[(6- Methyl- pyridazin-3- yl)methyl]-3- [(2- met...) Show SMILES Cc1cnc(s1)-c1cc(Oc2ccnc(C)c2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H21N5O2S/c1-14-4-5-19(28-27-14)13-25-22(29)17-9-18(23-26-12-16(3)31-23)11-21(10-17)30-20-6-7-24-15(2)8-20/h4-12H,13H2,1-3H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BEYER AKTIENGESELLSCHAFT US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10174016 (2019) BindingDB Entry DOI: 10.7270/Q2GB264F
					More data for this Ligand-Target Pair
P2X purinoceptor 2/3 (Homo sapiens (Human))	BDBM319934 (N-[(6- Methyl- pyridazin-3- yl)methyl]-3- [(2- met...) Show SMILES Cc1cnc(s1)-c1cc(Oc2ccnc(C)c2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H21N5O2S/c1-14-4-5-19(28-27-14)13-25-22(29)17-9-18(23-26-12-16(3)31-23)11-21(10-17)30-20-6-7-24-15(2)8-20/h4-12H,13H2,1-3H3,(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...				US Patent US10472354 (2019) BindingDB Entry DOI: 10.7270/Q2KD2197
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM319934 (N-[(6- Methyl- pyridazin-3- yl)methyl]-3- [(2- met...) Show SMILES Cc1cnc(s1)-c1cc(Oc2ccnc(C)c2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H21N5O2S/c1-14-4-5-19(28-27-14)13-25-22(29)17-9-18(23-26-12-16(3)31-23)11-21(10-17)30-20-6-7-24-15(2)8-20/h4-12H,13H2,1-3H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10202369 (2019) BindingDB Entry DOI: 10.7270/Q2TT4T2P
					More data for this Ligand-Target Pair
P2X purinoceptor 2/3 (Homo sapiens (Human))	BDBM319934 (N-[(6- Methyl- pyridazin-3- yl)methyl]-3- [(2- met...) Show SMILES Cc1cnc(s1)-c1cc(Oc2ccnc(C)c2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H21N5O2S/c1-14-4-5-19(28-27-14)13-25-22(29)17-9-18(23-26-12-16(3)31-23)11-21(10-17)30-20-6-7-24-15(2)8-20/h4-12H,13H2,1-3H3,(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10202369 (2019) BindingDB Entry DOI: 10.7270/Q2TT4T2P
					More data for this Ligand-Target Pair
P2X purinoceptor 3 (Homo sapiens (Human))	BDBM319934 (N-[(6- Methyl- pyridazin-3- yl)methyl]-3- [(2- met...) Show SMILES Cc1cnc(s1)-c1cc(Oc2ccnc(C)c2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H21N5O2S/c1-14-4-5-19(28-27-14)13-25-22(29)17-9-18(23-26-12-16(3)31-23)11-21(10-17)30-20-6-7-24-15(2)8-20/h4-12H,13H2,1-3H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Aktiengesellschaft US Patent					Assay Description A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...				US Patent US10472354 (2019) BindingDB Entry DOI: 10.7270/Q2KD2197
					More data for this Ligand-Target Pair
P2X purinoceptor 2 (Homo sapiens (Human))	BDBM319934 (N-[(6- Methyl- pyridazin-3- yl)methyl]-3- [(2- met...) Show SMILES Cc1cnc(s1)-c1cc(Oc2ccnc(C)c2)cc(c1)C(=O)NCc1ccc(C)nn1 Show InChI InChI=1S/C23H21N5O2S/c1-14-4-5-19(28-27-14)13-25-22(29)17-9-18(23-26-12-16(3)31-23)11-21(10-17)30-20-6-7-24-15(2)8-20/h4-12H,13H2,1-3H3,(H,25,29)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
BEYER AKTIENGESELLSCHAFT US Patent					Assay Description A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...				US Patent US10174016 (2019) BindingDB Entry DOI: 10.7270/Q2GB264F
					More data for this Ligand-Target Pair