BDBM320288 US10174024, Example 5::tert-Butyl 4-[3-(dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-oxan-4-yl(phenyl)methyl]-5H-pyrido[3,2-b]indol-8-yl]piperidine-1-carboxylate

SMILES: Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1ccc(cc21)C1CCN(CC1)C(=O)OC(C)(C)C

InChI Key: InChIKey=UPKWCVQVJFIELR-PGUFJCEWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320288 (US10174024, Example 5 | tert-Butyl 4-[3-(dimethyl-...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1ccc(cc21)C1CCN(CC1)C(=O)OC(C)(C)C |r| Show InChI InChI=1S/C37H44N6O3/c1-24-34(41(5)40-39-24)29-22-32-33(38-23-29)30-21-28(25-13-17-42(18-14-25)36(44)46-37(2,3)4)11-12-31(30)43(32)35(26-9-7-6-8-10-26)27-15-19-45-20-16-27/h6-12,21-23,25,27,35H,13-20H2,1-5H3/t35-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair