BDBM320289 1-{4-[3-(Dimethyl-1,2-oxazol-4-yl)-5-[(S)-oxan-4-yl(phenyl)methyl]-5H-pyrido[3,2-b]indol-8-yl]piperidin-1-yl}-2-hydroxyethan-1-one::US10174024, Example 6

SMILES: Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1ccc(cc21)N1CCN(CC1)C(=O)CO

InChI Key: InChIKey=UIMBYOKNVQGDKN-MGBGTMOVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 320289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM320289 (1-{4-[3-(Dimethyl-1,2-oxazol-4-yl)-5-[(S)-oxan-4-y...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1ccc(cc21)N1CCN(CC1)C(=O)CO |r| Show InChI InChI=1S/C33H37N7O3/c1-22-32(37(2)36-35-22)25-18-29-31(34-20-25)27-19-26(38-12-14-39(15-13-38)30(42)21-41)8-9-28(27)40(29)33(23-6-4-3-5-7-23)24-10-16-43-17-11-24/h3-9,18-20,24,33,41H,10-17,21H2,1-2H3/t33-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...				US Patent US10174024 (2019) BindingDB Entry DOI: 10.7270/Q2319XZ1
					More data for this Ligand-Target Pair